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Antibiotics are widely used in veterinary
medicine today. Louis Pasteur is generally credited for the discovery
of Penicillin from the mold penicillium. The word anti
means against, and the word bios means life, and thus
antibiotics are chemicals that are harmful to life. These drugs
are however only effective against bacteria and not viruses.
There are two types of antibiotics,
those that kill known as "cidal, and those that inhibit
growth are known as "static". Bactericidal drugs actively
destroy the cell wall of the bacteria while bacteriostatic drugs
work by limiting an essential ingredient that is required for the
normal functioning of a bacteria. The bactericidal group will act
more quickly to kill bacteria than the bacteriostatic group; however,
they often have more side effects, such as toxicity, than bacteriostatic
drugs do. Fortunately, over time, more and more sophisticated antibiotics
have been produced that have greatly deminished the concern for
side effects.
Bacteria have always had the ability
to develop resistance to the bacteriostatic group of antibiotics
more readily than the bactericidal group. This has resulted in many
frustrating experiences for the veterinarian and the owner. One
of the best ways to avoid resistance to an antibiotic is to give
the antibiotic at the correct dosage, at the proper interval and
for a long enough period of time.
Many years ago I was told that it
costs approximately 22 million dollars to bring a new veterinary
drug to market in this country due to the stringent requirements
of the Food and Drug Association. This may help to explain why drugs
cost the public so much. While generic companies can produce the
same drug for less money, once the patent has expired, they contribute
absolutely nothing towards the research and development of new and
better drugs for the future. Thus while it may be tempting to save
a few dollars and buy a generic drug today in the long run we will
ultimately pay a higher price for progress.
While it is true that there are always
bacteria on as well as in our bodies, not all of them are disease
producing or pathogenic. If an imbalance of bacteria occurs and
disease results, most antibiotics can quickly correct the problem.
Thus we have come to rely on these drugs to perform near miracles
in our pets as well as ourselves. I am glad we live in a modern
age!
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